Last revision: 01-21-23 By Eugene L. Heyden, RN “Immunoglobins are protein molecules that function as antibodies against many pathogenic as well as potential pathogenic microorganisms.”  ~Rountree, 2002 “SBI is uniquely composed of immunoglobulins which remain biologically active throughout the GI tract and have affinity for common intestinal antigens associated with GI inflammation.”  ~Detzel et al.,…

By Eugene L. Heyden, RN “Neuroinflammation plays an increasingly appreciated role in psychiatric disorders. SARS-CoV-2 is neuroinvasive and neuroinflammatory.  ~Alper, 2020, emphasis added “We report that both viral RNA and/or Spike protein remain in circulation long after acute infection (more than one-year post-infection in some cases) and this persistent circulation of viral components is associated…

Last update: 08-19-23 By Eugene L. Heyden, RN “Famotidine use was associated with a reduced risk of death and intubation. By comparison proton pump inhibitors (that reduce gastric acid independent of a histamine mechanism) were not associated with reduced risk of death or intubation.”  ~Hogan II et al., 2020 I like the sound of this! …

Last revision: 07-11-24 By Eugene L. Heyden, RN I appreciate your enthusiasm, I really do.  But may I suggest, next time, before you head out for a walk, you take the time to put on some clothing.  This the 21st Century, you know!  And I’m curious, how did you learn that both walking and sunshine…

By Eugene L. Heyden, RN I’m sure you’ve heard of Kelly by now.  Others have told her story, and you can find my version here, on my website.  And just so you don’t get the impression that Kelly is the only one who’s Crohn’s went into remission via vagal nerve stimulation (VNS), let me introduce…

Last revision: 02-18-24 By Eugene L. Heyden, RN It is now clear that opioid receptors participate in the function of the cells of the immune system, and evidence suggests that opioids modulate both innate and acquired immune responses.  ~ McCarthy et al., 2001 If you haven’t already heard, let me introduce you to low-dose Naltrexone…

  By Eugene L. Heyden, RN “Given the high prevalence and rising incidence of non-alcoholic fatty liver disease (NAFLD), the absence of approved therapies is striking. Although the mainstay of treatment of NAFLD is weight loss, it is hard to maintain, prompting the need for pharmacotherapy as well.”   ~Rotman and Sanyal, 2017 I’ve seen this…

[media-downloader media_id=”2384″ texts=”Download a PDF of entire article”] By Eugene L. Heyden, RN   Introduction The symptoms of long COVID are multifarious and include breathlessness, fatigue, chest pain, myalgia, cognitive dysfunction, innate immune responses coupled to inflammatory cytokine production, and a pro-coagulant state.  ~Kell et al., 2022, emphasis added) Ongoing vascular endothelial damage promotes platelet…

Last revision: 12-26-22 By Eugene L. Heyden, RN What does Adam know that you don’t know?  It may be what remission from Crohn’s feels like.  And if you were to ask him, he would say it feels “Great!”  It feels so great, in fact, he would like to tell you his story.  Particularly impressive, is…